Scientia Pharmaceutica

Volume 79 (2011) | Issue 3

Review

Neglected Disease – African Sleeping Sickness: Recent Synthetic and Modeling Advances
Sarvesh K. Paliwal, Ankita Narayan Verma, Shailendra Paliwal
389–428
Details | Full Text (pdf)

Original Papers and Short Communications

Pharmaceutical & Analytical Chemistry

Design, Synthesis and Biological Evaluation of Novel Pyrimido[4,5-d]pyrimidine CDK2 Inhibitors as Anti-tumor Agents
Samir M. El-Moghazy, Diaa A. Ibrahim, Nagwa M. Abdelgawad, Nahla A. H. Farag, Ahmad S. El-Khouly
429–447
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Design, Synthesis and Biological Evaluation of New 5,5-Diarylhydantoin Derivatives as Selective Cyclooxygenase-2 Inhibitors
Afshin Zarghi, Farin Sattary Javid, Razieh Ghodsi, Orkideh G. Dadrass, Bahram Daraei, Mehdi Hedayati
449–460
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Molecular Modeling on Structure-Function Analysis of Human Progesterone Receptor Modulators
Ria Pal, Md Ataul Islam, Tabassum Hossain, Achintya Saha
461–477
Details | Full Text (pdf) | Supporting Information (pdf, < 0.3 MB)

Preformulation Studies of Zidovudine Derivatives: Acid Dissociation Constants, Differential Scanning Calorimetry, Thermogravimetry, X-Ray Powder Diffractometry and Aqueous Stability Studies
Mónica A. Raviolo, Margarita C. Briñón
479–491
Details | Full Text (pdf)

Feed Forward Artificial Neural Network: Tool for Early Detection of Ovarian Cancer
Ankita Thakur, Vijay Mishra, Sunil K. Jain
493–505
Details | Full Text (pdf)

Synthesis of Diarylpyrazoles Containing a Phenylsulphone or Carbonitrile Moiety and their Chalcones as Possible Anti-Inflammatory Agents
Ekhlass Nassar, Hatem A. Abdel-Aziz, Hany S. Ibrahim, Ahmed M. Mansour
507–524
Details | Full Text (pdf)

A Rapid, Stability Indicating RP-UPLC Method for Simultaneous Determination of Ambroxol Hydrochloride, Cetirizine Hydrochloride and Antimicrobial Preservatives in Liquid Pharmaceutical Formulation
Rakshit Kanubhai Trivedi, Mukesh C. Patel, Sushant B. Jadhav
525–543
Details | Full Text (pdf)

Validated RP-HPLC Method for Simultaneous Quantitation of Losartan Potassium and Metolazone in Bulk Drug and Formulation
Ramkumar Dubey, Vidhya K. Bhusari, Sunil R. Dhaneshwar
545–554
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Detection, Isolation and Characterization of Principal Synthetic Route Indicative Impurities in Verapamil Hydrochloride
Viswanathan Srinivasan, Hariharan Sivaramakrishnan, Balakrishnan Karthikeyan
555–568
Details | Full Text (pdf)

Validation of a Flow Cytometry Based Binding Assay for Evaluation of Monoclonal Antibody Recognizing EGF Receptor
Mercedes Cedeño-Arias, Javier Sánchez-Ramírez, Rancés Blanco-Santana, Enrique Rengifo-Calzado
569–581
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Development and Validation of Amisulpride in Human Plasma by HPLC Coupled with Tandem Mass Spectrometry and its Application to a Pharmacokinetic Study
Ramakotaiah Mogili, Kanchanamala Kanala, Balasekhara Reddy Challa, Babu Rao Chandu, Chandrasekhar Kottapalli Bannoth
583–599
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Synthesis, Characterization and Quantification of Simvastatin Metabolites and Impurities
Manish S. Bhatia, Swapnil D. Jadhav, Neela M. Bhatia, Prafulla B. Choudhari, Kundan B. Ingale
601–614
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Pharmacology & Clinical Pharmacy

In Vitro and In Vivo Effects of Natural Putative Secretagogues of Glucagon-Like Peptide-1 (GLP-1)
Eamon P. Rafferty, Alastair R. Wylie, Chris T. Elliott, Olivier P. Chevallier, David J. Grieve, Brian D. Green
615–621
Details | Full Text (pdf)

Type 2 Diabetes Mellitus-Induced Hyperglycemia in Patients with NAFLD and Normal LFTs: Relationship to Lipid Profile, Oxidative Stress and Pro-Inflammatory Cytokines
Mohamed E. E. Shams, Mohammed M. H. Al-Gayyar, Enaase A. M. E. Barakat
623–634
Details | Full Text (pdf)

Pharmaceutical Technology & Biopharmaceutics

Enhanced Antihypertensive Activity of Candesartan Cilexetil Nanosuspension: Formulation, Characterization and Pharmacodynamic Study
Chetan Detroja, Sandip Chavhan, Krutika Sawant
635–651
Details | Full Text (pdf)

Taste Masked Microspheres of Ofloxacin: Formulation and Evaluation of Orodispersible Tablets
Karan Malik, Gurpreet Arora, Inderbir Singh
653–672
Details | Full Text (pdf)

Amoxicillin Loaded Chitosan–Alginate Polyelectrolyte Complex Nanoparticles as Mucopenetrating Delivery System for H. Pylori
Saahil Arora, Sankalp Gupta, Raj K. Narang, Ramji D. Budhiraja
673–694
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Editorial

The Successful Relaunch of Scientia Pharmaceutica Continues Achieving Success
Wolfgang Kubelka, Gernot A. Eller
695–699
Details | Full Text (pdf)

Book Reviews

"Characterization of Nanoparticles Intended for Drug Delivery"
701
Full Text (pdf)

"Teedrogen und Phytopharmaka"
703
Full Text (pdf)