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Sci. Pharm. 2013; 81: 251–258

Assessment of Anti-Quorum Sensing Activity for Some Ornamental and Medicinal Plants Native to Egypt

Ahmed A. ZAKI 1, Mona I. SHAABAN 2, Nadia E. HASHISH * 1, Mohamed A. AMER 1, Mohamed-Farid LAHLOUB 1

1 Pharmacognosy department, Faculty of Pharmacy, Mansoura University, 35516, Egypt.
2 Microbiology department, Faculty of Pharmacy, Mansoura University, 35516, Egypt.

* Corresponding author. E-mail: (N. E. Hashish)


This study investigated the effects of some plant extracts on the bacterial communication system, expressed as quorum sensing (QS) activity. Quorum sensing has a directly proportional effect on the amount of certain compounds, such as pigments, produced by the bacteria. Alcohol extracts of 23 ornamental and medicinal plants were tested for anti-QS activity by the Chromobacterium violaceum assay using the agar cup diffusion method. The screening revealed the anti-QS activity of six plants; namely the leaves of Adhatoda vasica Nees, Bauhinia purpurea L., Lantana camara L., Myoporum laetum G. Forst.; the fruits of Piper longum L.; and the aerial parts of Taraxacum officinale F.H. Wigg.


Antimicrobial agents Antiquorum sensing Herbal extracts

Received April 30th, 2012 | Accepted November 5th, 2012 | Published Online November 5th, 2012